https://www.danwjoyce.com/blog daily 0.75 2024-09-07 https://www.danwjoyce.com/blog/2022/6/21/some-thoughts-on-big-data-ai-and-psychiatry monthly 0.5 2022-06-21 https://www.danwjoyce.com/blog/2021/3/14/receptorligand-profile-tool monthly 0.5 2021-03-14 https://www.danwjoyce.com/blog/2020/4/8/decisions-and-loss-functions-a-more-clinical-focus monthly 0.5 2020-04-08 https://www.danwjoyce.com/blog/2020/3/30/loss-risk-and-posterior-distributions monthly 0.5 2020-03-30 https://www.danwjoyce.com/blog/2019/6/27/routines-and-workflow-adaptations-around-the-electronic-health-record monthly 0.5 2019-06-27 https://www.danwjoyce.com/blog/2019/5/12/clinical-state-and-dynamical-systems monthly 0.5 2019-05-12 https://www.danwjoyce.com/blog/2018/6/7/visualising-pharmacology-part-four monthly 0.5 2018-08-03 https://images.squarespace-cdn.com/content/v1/57efe37e6a4963a42b25c646/1532786135961-OOY5SG1O68QLXYPOE4A9/DA1-4_combined_part4.png Blog - Similarity Maps for Antipsychotic Medications - Part Four Figure One : DA similarity map (from 4D to 2D). The Overall Affinity colouring represents the sum of DA1-DA4 affinities for each medication. https://images.squarespace-cdn.com/content/v1/57efe37e6a4963a42b25c646/1532786410335-02SBDBERN86RRSZS9JS7/compress_DA_2D_to_1D.gif Blog - Similarity Maps for Antipsychotic Medications - Part Four Figure Two : Compressing DA distances into 1D https://images.squarespace-cdn.com/content/v1/57efe37e6a4963a42b25c646/1532786849559-NKCAN1D563PN4CG8BCXF/compress_5HT_2D_to_1D.gif Blog - Similarity Maps for Antipsychotic Medications - Part Four Figure Four : Compressing 5HT distances into 1D https://images.squarespace-cdn.com/content/v1/57efe37e6a4963a42b25c646/1532786731180-4EAL4T8TKP0HXWR5H1UG/5HT-1-2-6-7_combined_part4.png Blog - Similarity Maps for Antipsychotic Medications - Part Four Figure Three : 5HT distances, from 5D to 2D. The Overall Affinity colouring represents the sum of 5HT1A, 2A, 2C, 6 and 7 affinities for each medication. https://images.squarespace-cdn.com/content/v1/57efe37e6a4963a42b25c646/1532787533323-886QRKOPV57GHI28QEUV/DA_NN_Combined-1D_DA_5HT_part4.png Blog - Similarity Maps for Antipsychotic Medications - Part Four https://images.squarespace-cdn.com/content/v1/57efe37e6a4963a42b25c646/1534547946129-LMRISC2OUAYSUE1HFYV8/5HT1-7_2D_antipsy_sim_map.png Blog - Similarity Maps for Antipsychotic Medications - Part Four https://images.squarespace-cdn.com/content/v1/57efe37e6a4963a42b25c646/1532787182291-2B98HCQ1BCYBIEV27T8V/DA-5HT-space.gif Blog - Similarity Maps for Antipsychotic Medications - Part Four Figure Five : deriving a representation map from 1D embeddings of DA and 5HT; the overall affinity colour represents the sum of both 5HT and DA receptor affinities. https://www.danwjoyce.com/blog/2018/6/7/visualising-pharmacology-part-three monthly 0.5 2018-07-25 https://images.squarespace-cdn.com/content/v1/57efe37e6a4963a42b25c646/1532284523953-FTR1K1N8Q4KBPKITVOFU/DA_quant_table.png Blog - Similarity Maps for Antipsychotic Medications - Dopamine and Serotonin Receptor Affinities : Part Three https://images.squarespace-cdn.com/content/v1/57efe37e6a4963a42b25c646/1532284523765-3TJOY3GIGILH85WGQZCW/5HT_quant_table.png Blog - Similarity Maps for Antipsychotic Medications - Dopamine and Serotonin Receptor Affinities : Part Three https://images.squarespace-cdn.com/content/v1/57efe37e6a4963a42b25c646/1532516685026-PACHEI7136DYD0AK0MYU/DA1-DA4_2D_antipsy_sim_map.png Blog - Similarity Maps for Antipsychotic Medications - Dopamine and Serotonin Receptor Affinities : Part Three Figure One : AMI = AMISULPRIDE; ARI = ARIPIPRAZOLE; ASE = ASENAPINE; BRE = BREXPIPRAZOLE; CHL = CHLORPROMAZINE; CLO = CLOZAPINE; FLU = FLUPENTHIXOL; HAL = HALOPERIDOL; ILO = ILOPERIDONE; LOX = LOXAPINE; LUR = LURASIDONE; MEL = MELPERONE; OLA = OLANZAPINE; PER = PERPHENAZINE; PIM = PIMOZIDE; QUE = QUETIAPINE; RIS = RISPERIDONE; SER = SERTINDOLE; SUL = SULPIRIDE; TRI = TRIFLUOPERAZINE; ZIP = ZIPRASIDONE https://images.squarespace-cdn.com/content/v1/57efe37e6a4963a42b25c646/1532517052221-5L2LP1UH9KQTBS7I49BV/5HT1-7_2D_antipsy_sim_map.png Blog - 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